Actively Recruiting
External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
Led by Medical College of Wisconsin · Updated on 2026-01-14
60
Participants Needed
1
Research Sites
628 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.
CONDITIONS
Official Title
External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy volunteers must be at least 18 years of age or older.
You will not qualify if you...
- Subjects with cervical spine disorders.
- Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease
- Subjects with carotid artery bruit or carotid vascular disorders.
- Subjects suffering from muscle diseases like muscular dystrophies, myopathies.
- Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
- Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation.
- Subjects cannot have previous head or neck surgery or radiation.
- Subjects unable to tolerate nasal intubation.
- Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated.
- Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe.
- Subjects with autonomic dysfunction.
- Subjects having a history of allergy to lidocaine and barium.
- Subjects who are pregnant or lactating.
- Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.).
- Subjects who are medically unstable.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53086
Actively Recruiting
Research Team
R
Reza Shaker, MD
CONTACT
M
Mark Kern
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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