Actively Recruiting

Age: 18Years - 44Years
FEMALE
NCT06788977

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

Led by Cefaly Technology · Updated on 2026-04-15

550

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This online registry aims to understand the potential benefits and safety of external trigeminal nerve stimulation for the treatment of migraine in pregnant women. Women do not need to use external trigeminal nerve stimulation or any other form of migraine treatment to participate in the registry. The main question it aims to answer is: Is external trigeminal nerve stimulation a safe and effective option for migraine treatment during and after pregnancy? There are no required changes in migraine treatment to participate in this registry. Participants may or may not use external trigeminal nerve stimulation or any other treatment they currently use and may still participate in the registry. There are no clinic or research visits, as the registry is entirely online. Participants will be asked to complete up to six 15- 20-minute surveys over a time period of up to 12 months.

CONDITIONS

Official Title

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

Who Can Participate

Age: 18Years - 44Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing and able to provide simple consent for registry participation
  • Has access to email, text messages via smartphone or computer with internet access
  • Between 18 to 44 years old at enrollment
  • Pregnant with one fetus/baby (singleton pregnancy) at enrollment
  • Has headaches or migraines before pregnancy and continuing into pregnancy, or started headaches or migraines in the first trimester
  • Able to provide proof of active intrauterine pregnancy and estimated due date by uploading one of the following: ultrasound report, beta hCG lab report, provider's medical documentation confirming pregnancy with fetal heart sounds and due date, or a provider's note on prescription sheet or letterhead confirming pregnancy and due date
Not Eligible

You will not qualify if you...

  • Under 18 or over 44 years old at enrollment
  • Not pregnant at enrollment
  • Pregnant with more than one fetus/baby (multigestational pregnancy) at enrollment
  • Any condition that would prevent participation as judged by the patient's physician or study investigator
  • No access to email, smartphone, or computer with internet

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

https://public.smart-trial.co/#/public/649d77f0e8f8d0fb993d0c61/6626f6a04f0a3c7dd0860e14/662726d84f0a3c7dd08aeaa0/signup?lang=en-us&enforceLanguage=true

Darien, Connecticut, United States, 06820

Actively Recruiting

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Research Team

M

Michael A.L. Johnson, MD

CONTACT

G

Gregory Panza, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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