Actively Recruiting
Extracellular Vesicles in Fibrin Gel for Cartilage Repair
Led by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Updated on 2024-12-03
51
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project aims to produce and study in vitro/ex vivo a platelet rich plasma (PRP)-derived fibrin gel loaded with mesenchymal stromal cells (MSC)-extracellular vesicles (EVs), to combine the positive results on cartilage growth of PRP growth factors and the hyaline cartilage stimulating activity of MSC-EVs. Therefore, the project goal is to provide an advanced option for orthopedic patients with an innovative evolution of a gold standard procedure, making it easy to translate into daily clinical practice for physicians, healthcare professionals and patients.
CONDITIONS
Official Title
Extracellular Vesicles in Fibrin Gel for Cartilage Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females 18 years or older
- Patients undergoing plastic surgery procedures
- Patients undergoing elective joint surgery with knee or hip osteoarthritis (any Kellgren-Lawrence grade)
- Patients undergoing regenerative medicine treatments with PRP for knee or hip osteoarthritis (any Kellgren-Lawrence grade)
- Signed informed consent for the study
You will not qualify if you...
- Positive virological test for HIV, HCV, HBV, or TPHA
- Pregnancy or breastfeeding by self-declaration
- Other conditions deemed unsuitable by the investigator or physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Milan, MI, Italy, 20157
Actively Recruiting
Research Team
G
Giuseppe Peretti
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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