Comparing Single-Port Extraperitoneal and Multi-Port Transperitoneal Robotic-Assisted Radical Prostatectomy for Localized Prostate Cancer A Randomized Study of Functional Recovery and Outcomes

What this Trial Is About

Researchers are conducting a multicenter, randomized controlled clinical trial to compare two types of robotic-assisted radical prostatectomy surgeries for men with localized prostate cancer. The study aims to determine if single-port extraperitoneal VIP robotic prostatectomy is as effective as the multi-port transperitoneal approach in terms of functional recovery and other important outcomes. This trial will enroll 480 patients aged 18 to 75 years with specific prostate cancer characteristics and follow them for one year after surgery. Participants are randomly assigned to receive either single-port extraperitoneal robotic-assisted radical prostatectomy using Vattikuti Institute Prostatectomy VIP techniques or multi-port transperitoneal robotic-assisted radical prostatectomy with bilateral intrafascial nerve-sparing techniques. The study records perioperative data and monitors patients closely during treatment and follow-up visits over the course of one year to assess recovery and other clinical outcomes. During the trial, participants will undergo evaluations including assessments of potency and continence recovery at multiple time points up to one year after surgery. Other measures include PSA levels, complication scores, operative time, blood loss, number of additional ports used during surgery, and length of hospital stay. The research team carefully monitors all data to compare the effectiveness and safety of the two surgical methods while ensuring participants complete scheduled follow-up visits.

Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)