Study on Respiratory Health and Development in Preterm Infants Born Before 29 Weeks

What this Trial Is About

Researchers are studying the respiratory outcomes of preterm infants born before 29 weeks of gestation, focusing on how various factors affect their lung function and long-term health. The study also looks at growth and developmental progress in these infants, aiming to improve prevention and treatment of chronic respiratory diseases. This observational research collects detailed clinical data and biological samples to better understand risks and outcomes. Participants are preterm infants enrolled within 7 days of birth at participating hospitals. The study involves reviewing medical records during hospitalization and following infants through 24 months corrected age. Surveys are conducted with parents at 4, 8, and 12 months corrected age, and outpatient visit records are analyzed at 12 and 24 months. When direct follow-up is challenging, information may be collected via phone, text, email, or web surveys. Throughout the study, researchers assess respiratory symptoms, medication use, hospitalizations, growth, and developmental milestones. The main outcome is the evaluation of postprematurity respiratory disease at 12 months corrected age. Additional assessments include growth and development at 24 months and long-term respiratory outcomes at 6 years. The study aims to create a comprehensive database to support better care strategies for these vulnerable infants.

Extremely Preterm Respiratory Outcome Cohort