Actively Recruiting
Extrinsic and Intrinsic Factors in Atopic Dermatitis Upon Systemic Immune Modulation
Led by Charite University, Berlin, Germany · Updated on 2024-08-21
25
Participants Needed
1
Research Sites
378 weeks
Total Duration
On this page
Sponsors
C
Charite University, Berlin, Germany
Lead Sponsor
S
Sanofi
Collaborating Sponsor
AI-Summary
What this Trial Is About
Currently, patients with moderate to severe atopic dermatitis are treated with dupilumab if unresponsive to topical treatment. However, not all patients who suffer from atopic dermatitis respond similarly to this treatment. Pattern recognition of immune cells (PRI) is an efficient method to screen patients to allow a more personalized therapy. The main aim of this scientific explorative study is to unravel the changes in peripheral blood immune cell compositions in patients with atopic eczema undergoing dupilumab treatment. This allows the identification of phenotypes of treatment responders and non-responders and possible approaches of treatment modifications for non-responders.
CONDITIONS
Official Title
Extrinsic and Intrinsic Factors in Atopic Dermatitis Upon Systemic Immune Modulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 and above
- Diagnosis of atopic dermatitis for 651 year
- Inadequate response to treatment with topical medications
- Confirmed dupilumab treatment
You will not qualify if you...
- Age below 18
- Known or suspected allergy or reaction to any component of the dupilumab formulation
- Known active allergic or irritant contact dermatitis that is likely to interfere with the assessment of the severity of AD
- Severe conjunctivitis or blepharitis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dpt of Dermatology and Allergology, Charité - Universitätsmedizin Berlin
Berlin, Germany, 10117
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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