Actively Recruiting
EXtubation Related Complications - the EXTUBE Study (EXTUBE)
Led by University Health Network, Toronto · Updated on 2026-04-24
3000
Participants Needed
28
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
EXTUBE is an international, multicentre, prospective cohort study evaluating the incidence, risk factors, and outcomes of extubation-related complications and describing clinical practices related to extubation after general anesthesia or after critical illness in the operating room (OR), out of OR anesthesia location or intensive care unit (ICU).
CONDITIONS
Official Title
EXtubation Related Complications - the EXTUBE Study (EXTUBE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (≥18 years old)
- Undergoing extubation of an endotracheal tube (including index extubation and re-extubations) after general anesthesia in the OR, out of OR anesthesia location or ICU
- Undergoing extubation during the specified enrollment window
You will not qualify if you...
- Extubation performed in the context of withdrawal of life support measures
- Extubation performed for tracheostomy decannulation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 28 locations
1
Banner University Medical Centre
Tucson, Arizona, United States, 85724-5114
Completed
2
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Completed
3
University of Florida
Gainesville, Florida, United States, 32608
Completed
4
The University of Chicago
Chicago, Illinois, United States, 60637
Active, Not Recruiting
5
Oregon Health & Science University
Portland, Oregon, United States, 97239
Completed
6
The University of Texas Health Science Center
Houston, Texas, United States, 77030
Completed
7
Royal North Shore Hospital
Sydney, New South Wales, Australia, 2065
Completed
8
The Northern Hospital
Melbourne, Victoria, Australia, 3076
Completed
9
Austin Hospital
Melbourne, Victoria, Australia, 3084
Completed
10
Eastern Health - Box Hill Hospital
Melbourne, Victoria, Australia, 3128
Completed
11
Eastern Health - Maroondah Hospital
Melbourne, Victoria, Australia, 3135
Completed
12
Eastern Health - Angliss Hospital
Melbourne, Victoria, Australia, 3156
Completed
13
Surrey Memorial Hospital
Surrey, British Columbia, Canada, V3V 1Z2
Completed
14
The Moncton Hospital
Moncton, New Brunswick, Canada, E1C 4B7
Completed
15
Sunnybrook Hospital
North York, Ontario, Canada, M4N 3M5
Completed
16
Niagara Health - Marotta Family Hospital
Saint Catharines, Ontario, Canada, L2S 0A9
Completed
17
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8
Completed
18
Mount Sinai Hospital
Toronto, Ontario, Canada, M5G 1X5
Completed
19
University Health Network - Toronto General Hospital
Toronto, Ontario, Canada, M5G 2C4
Completed
20
University Health Network - Toronto Western Hospital
Toronto, Ontario, Canada, M5T 2S8
Completed
21
Centre hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, Canada, H2X 0C1
Active, Not Recruiting
22
Cork University Hospital
Cork, Ireland, T12 DFK4
Actively Recruiting
23
Mater Misericordiae University Hospital
Dublin, Ireland, D07 R2WY
Actively Recruiting
24
Galway University Hospitals
Galway, Ireland, H91 YR71
Completed
25
Southland Hospital
Invercargill, New Zealand, 9812
Actively Recruiting
26
Tan Tock Seng Hospital
Singapore, Singapore, 308433
Completed
27
Royal United Hospitals Bath
Bath, United Kingdom, BA1 3NG
Completed
28
Freeman Hospital
Newcastle upon Tyne, United Kingdom, NE7 7DN
Completed
Research Team
M
Matteo Parotto, MD, PhD
CONTACT
S
Shayan Wasim, MPH, BSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here