Actively Recruiting
Eye-Brain-Kidney in CKD
Led by Beijing Friendship Hospital · Updated on 2026-01-27
1500
Participants Needed
1
Research Sites
317 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is: Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.
CONDITIONS
Official Title
Eye-Brain-Kidney in CKD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18-70 years
- Clinically diagnosed with Chronic Kidney Disease stages 1 to 5
- No contraindications for MRI and able to complete MRI scans (e.g., no pacemaker, no claustrophobia, no cochlear implant, no hearing aid, no coronary stents implanted before 2015)
You will not qualify if you...
- Recent or prior cerebral hemorrhage or cerebral infarction
- History of epileptic seizures or psychiatric disorders
- Claustrophobia
- Pregnant or lactating
- Other central nervous system diseases (e.g., tumor, trauma)
- Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction
- Any systemic or other diseases unsuitable for trial participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100050
Actively Recruiting
Research Team
H
Hao Wang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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