Actively Recruiting
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
Led by Shanghai Changzheng Hospital · Updated on 2026-02-06
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating eye health and visual function in people with Thyroid-Associated Ophthalmopathy (TAO), a condition that can cause bulging eyes and limited eye movement. This study aims to use non-invasive eye-tracking technology to measure how TAO affects eye movement and visual attention compared to healthy individuals. The goal is to objectively understand how the disease impacts physical eye function and social behaviors like eye contact. Participants will undergo a single, standardized visit where they will complete a visual function assessment using a desktop high-frequency eye tracker. The test includes calibration to ensure accurate tracking, oculomotor tasks to evaluate eye stability and smooth pursuit ability, and visual attention tasks to record how participants scan static images. This process is non-invasive and takes about 15 to 20 minutes. During the visit, researchers will record gaze patterns and measure outcomes such as smooth pursuit function, central fixation stability, gaze distribution on eye areas, and extraocular muscle thickness. These measures will help quantify the disease's effects. The study will include 100 participants, both patients with TAO and healthy volunteers, aged 18 to 70 years. The entire participation involves this brief assessment without any treatment or further follow-up.
CONDITIONS
Brief Title
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 70 years, inclusive
- Willing and able to provide written informed consent
- Best-corrected visual acuity (BCVA) 21 1.0 in both eyes, with no history of ocular diseases or thyroid disorders
You will not qualify if you...
- History of non-TAO ocular motility disorders such as myasthenia gravis, cranial nerve palsy, or congenital strabismus
- Neurological diseases affecting eye movement control (e.g., Parkinson's, multiple sclerosis, stroke, brain tumors)
- Significant visual impairment with BCVA < 0.5 due to media opacities or retinopathy
- Prior ocular surgery affecting extraocular muscle mechanics (e.g., strabismus surgery, scleral buckling)
- Psychiatric or cognitive disorders affecting ability to follow instructions or eye movements (e.g., schizophrenia)
- Use of medication affecting reaction time (e.g., sedatives) within 48 hours of testing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a non-invasive eye tracking assessment to evaluate eye movement function and visual attention patterns.
1 study visit lasting approximately 15-20 minutes (in-person)
Trial Site Locations
Total: 1 location
1
Changzheng Hospital
Shanghai, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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