Clinically accessible eye-tracking in thyroid-associated ophthalmopathy: exploratory classification modeling and gaze allocation to disease-related periocular images.
Chunhui Yang, Ya Shen, Jian Song...
https://pubmed.ncbi.nlm.nih.gov/42332638/Actively Recruiting
Led by Shanghai Changzheng Hospital · Updated on 2026-02-06
100
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating eye health and visual function in people with Thyroid-Associated Ophthalmopathy TAO, a condition that can cause bulging eyes and limited eye movement. This study aims to use non-invasive eye-tracking technology to measure how TAO affects eye movement and visual attention compared to healthy individuals. The goal is to objectively understand how the disease impacts physical eye function and social behaviors like eye contact. Participants will undergo a single, standardized visit where they will complete a visual function assessment using a desktop high-frequency eye tracker. The test includes calibration to ensure accurate tracking, oculomotor tasks to evaluate eye stability and smooth pursuit ability, and visual attention tasks to record how participants scan static images. This process is non-invasive and takes about 15 to 20 minutes. During the visit, researchers will record gaze patterns and measure outcomes such as smooth pursuit function, central fixation stability, gaze distribution on eye areas, and extraocular muscle thickness. These measures will help quantify the diseases effects. The study will include 100 participants, both patients with TAO and healthy volunteers, aged 18 to 70 years. The entire participation involves this brief assessment without any treatment or further follow-up.
CONDITIONS
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Shanghai Changzheng Hospital
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a non-invasive eye tracking assessment to evaluate eye movement function and visual attention patterns.
1 study visit lasting approximately 15-20 minutes (in-person)
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Chunhui Yang, Ya Shen, Jian Song...
https://pubmed.ncbi.nlm.nih.gov/42332638/Shanghai Changzheng Hospital
Lead Sponsor