Actively Recruiting
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
Led by Shanghai Changzheng Hospital · Updated on 2026-02-06
100
Participants Needed
1
Research Sites
169 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study focuses on eye health and visual function in patients with Thyroid-Associated Ophthalmopathy (TAO), a condition that often causes bulging eyes and restricted eye movement. The purpose of this study is to use non-invasive eye-tracking technology to evaluate how the disease affects eye movement function. The investigators hypothesize that compared to healthy individuals, patients with TAO will show measurable differences in eye stability and the ability to track moving objects. Additionally, the investigators believe the disease may alter how patients visually scan faces (e.g., avoiding eye contact). The study will enroll 100 participants, including both patients and healthy volunteers. By recording gaze patterns while participants look at a screen, the investigators aim to objectively quantify the physical and social impact of the disease, providing better data for future treatment plans.
CONDITIONS
Official Title
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 70 years, inclusive.
- Willing and able to provide written informed consent.
- Best-corrected visual acuity (BCVA) 61.0 in both eyes, with no history of ocular diseases or thyroid disorders.
You will not qualify if you...
- History of non-TAO ocular motility disorders such as myasthenia gravis, cranial nerve palsy, or congenital strabismus.
- Presence of neurological diseases affecting oculomotor control including Parkinson's disease, multiple sclerosis, stroke, or brain tumors.
- Significant visual impairment with BCVA less than 0.5 due to media opacities or retinopathy preventing clear visualization of stimuli.
- Previous ocular surgery affecting extraocular muscle mechanics such as strabismus surgery or scleral buckling.
- Psychiatric or cognitive disorders that impair ability to follow instructions or affect eye movements, including schizophrenia.
- Use of medications affecting reaction time, such as sedatives, within 48 hours prior to testing.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Changzheng Hospital
Shanghai, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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