Actively Recruiting

All Genders
Healthy Volunteers
NCT05294978

EyeConic: Qualification for Cone-Optogenetics

Led by Institute of Molecular and Clinical Ophthalmology Basel · Updated on 2025-07-31

1000

Participants Needed

9

Research Sites

282 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.

CONDITIONS

Official Title

EyeConic: Qualification for Cone-Optogenetics

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of generalized inherited retinal dystrophy (IRD)
  • Low vision defined as visual acuity worse or equal to 0.05 (or 20/400) in the study eye
  • Availability of macular optical coherence tomography (OCT) data for patients
  • Normal ophthalmic findings for control participants
  • Availability of macular optical coherence tomography (OCT) data for controls
Not Eligible

You will not qualify if you...

  • Presence of other eye diseases significantly affecting vision or retinal structure
  • Presence of extraocular diseases affecting retinal structure such as neurodegenerative diseases

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

University of California San Francisco, Department of Ophthalmology

San Francisco, California, United States, 94158

Actively Recruiting

2

Bascom Palmer Eye Institute

Miami, Florida, United States, 33136

Actively Recruiting

3

University of Pittsburgh, Department of Ophthalmology

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

4

Beijing Institute of Ophthalmology

Beijing, China

Actively Recruiting

5

Universitätsklinikum Tübingen Augenklinik

Tübingen, Germany

Actively Recruiting

6

Semmelweis University, Department of Ophthalmology

Budapest, Hungary

Actively Recruiting

7

Oculista Ospedale Parma

Parma, Italy

Actively Recruiting

8

University Hospital Basel, Eye Clinic

Basel, Switzerland, 4031

Actively Recruiting

9

Moorfields Eye Hospital

London, United Kingdom

Actively Recruiting

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Research Team

L

Lucas Janeschitz-Kriegl, MD

CONTACT

T

Tiana Koottungal

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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EyeConic: Qualification for Cone-Optogenetics | DecenTrialz