Actively Recruiting
F 18 T807 Tau PET Imaging of Alzheimer's Disease
Led by Tammie L. S. Benzinger, MD, PhD · Updated on 2024-07-17
900
Participants Needed
1
Research Sites
527 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A single-center, open-label baseline controlled imaging study designed to assess whether brain tau fibril uptake of flortaucipir as measured by PET correlates with cognitive status of individuals with and without brain tau fibrils.
CONDITIONS
Official Title
F 18 T807 Tau PET Imaging of Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female participants, at least 18 years of age.
- Cognitively normal or with mild dementia, as clinically assessed.
- Able and willing to undergo MRI or CT, PET scans, radioactive tracer injection, and lumbar puncture if chosen.
- Pre-menopausal women must have a urine pregnancy test within 24 hours before drug administration.
You will not qualify if you...
- Any condition that increases risk, limits ability to tolerate procedures, or interferes with data collection (e.g., severe chronic back pain).
- Unable or unlikely to complete imaging procedures.
- High risk for Torsades de Pointes or taking medications that prolong QT interval.
- Hypersensitivity to F 18 T807 or its excipients.
- Contraindications to PET, PET-CT, or MRI (e.g., electronic medical devices, inability to lie still).
- Severe claustrophobia.
- Currently pregnant or breastfeeding.
- On anticoagulant therapy if undergoing optional lumbar puncture.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
K
Kelley M Jackson, BA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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