Testing a Facial Expression-Based Personalization Tool to Improve Engagement in Computerized Cognitive Training for Older Adults at Risk for Alzheimers Disease

What this Trial Is About

Researchers are studying how to improve adherence to computerized cognitive training done at home by older adults at risk for Alzheimers disease or related dementias. This study tests a facial expression-based personalization engine FPE designed to monitor and adjust training in real time, aiming to keep participants effectively engaged and enhance long-term adherence. The study compares cognitive training programs with and without this FPE in older adults at risk for cognitive decline. Participants will engage in a six-week unsupervised cognitive training program called speed of processing training. One group will use the FPE system that tracks facial expressions to assess engagement and modulates task novelty accordingly, while the other group will use traditional computerized cognitive training without this personalized feedback. The study evaluates how this approach influences engagement and adherence. Throughout the intervention, researchers will measure a multi-modal effective engagement index continuously over up to eight weeks. Other assessments include time spent training, self-reported fatigue, memory, and executive function at baseline, post-intervention, and at follow-up six weeks later. The study is randomized and double-blind, with participation possible for adults aged 60 to 89, and includes monitoring to understand how engagement impacts cognitive outcomes.

FACE Phase II (a Stage II Trial)