Actively Recruiting

All Genders
NCT07422454

FACE.S-4-KIDS : A Deep Phenotyping Database of Craniofacial Anomalies During Development With 4 Pilot Projects

Led by Imagine Institute · Updated on 2026-02-20

3100

Participants Needed

1

Research Sites

419 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

FACE.S-4-KIDS is an ambitious database project addressing the scientific question of the variable expression of craniofacial disorders in humans, to reach a sound clinical management (diagnosis, prognosis), and the establishment of personalised treatment plans.

CONDITIONS

Official Title

FACE.S-4-KIDS : A Deep Phenotyping Database of Craniofacial Anomalies During Development With 4 Pilot Projects

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with craniostenosis linked to FGFR signaling, achondroplasia, hypochondroplasia, osteogenesis imperfecta, or Pierre Robin sequence (with or without anatomical markers)
  • Patients who have consented to the storage of biological samples in relevant collections such as Chondroplasia and craniostenosis, Constitutional Bone Diseases, or Developmental anomalies
  • Patients who have undergone craniofacial imaging (CT or MRI) as part of their care
  • Control patients seen at Genetics, Pediatrics, or Maxillofacial Surgery Departments at Necker without the above pathologies
  • Control patients who have undergone genome sequencing and consented to biological sample storage in the Infectious Diseases collection
  • Control patients who have had craniofacial imaging (CT or MRI) as part of their care
Not Eligible

You will not qualify if you...

  • Patients or their parents who oppose the reuse of their medical data for this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pr Stanislas Lyonnet

Paris, France

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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FACE.S-4-KIDS : A Deep Phenotyping Database of Craniofacial Anomalies During Development With 4 Pilot Projects | DecenTrialz