Actively Recruiting

Age: 18Years - 99Years
All Genders
Healthy Volunteers
ID01612949

Comparison of a Computerized Image Analysis to Conventional Airway Examination Techniques to Predict Difficult Endotracheal Intubation

Led by Wake Forest University Health Sciences · Updated on 2026-04-01

3500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a computer algorithm designed to predict how easy or difficult it is to perform endotracheal intubation by analyzing digital photographs of a patient's face from three different angles. This study compares the algorithm's predictions with traditional airway assessment techniques to improve accuracy and patient safety during intubation procedures. The study includes patients who are easy or difficult to intubate, based on specific surgical criteria and anesthetic records. Participants are divided into groups for model development and validation, including those identified as easy or difficult to intubate and a group without prior intubation difficulty classification. Photographs of the head and neck are taken from the front, left, and right sides, which are then analyzed using facial structure software to create face models. The study also allows for intubation attempts using either a Macintosh or Miller laryngoscope blade, with the aim to assess facial features predictive of difficulty with different blades. During the study, participants undergo photographic imaging of their head and neck, and their intubation outcomes are recorded at surgery. Researchers will compare the algorithm's ability to predict intubation difficulty against conventional tests by analyzing the images and surgical outcomes over approximately two years. The study tracks whether the algorithm can statistically differentiate between easy and difficult intubation cases and tests the reproducibility of the developed models to improve clinical acceptance and patient safety.

CONDITIONS

Brief Title

Facial Analysis to Classify Difficult Intubation

Who Can Participate

Age: 18Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients requiring endotracheal intubation
  • Patients consenting to acquisition of photographic images of the head and neck
Not Eligible

You will not qualify if you...

  • Patients who had undergone head or neck surgery
  • Patients in whom central venous catheters or other interventions prevent full view of the face in frontal and profile views
  • Patients who were neither easy nor difficult to intubate by study criteria

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to surgery day

Participants undergo photographing of the head and neck from multiple angles. These photographs are analyzed by facial structure software to create a face model for predicting intubation difficulty.

1 visit (in-person)

Monitoring

Duration - Approximately 2 years, based on current enrollment pattern

Participants are observed during their surgical intubation to determine ease or difficulty of intubation, which is used to validate the facial analysis algorithm.

Observations occur during routine surgical care

Trial Site Locations

Total: 1 location

1

Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, United States, 27157

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Research Team

S

Scott Segal, MD, MHCM

A

Angela Goodson

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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Published Research Related To This Trial

Identification of difficult to intubate patients from frontal face images using an ensemble of deep learning models.

Thomas E Tavolara, Metin N Gurcan, Scott Segal...

https://pubmed.ncbi.nlm.nih.gov/34391000