Actively Recruiting
Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation
Led by University Hospital, Clermont-Ferrand · Updated on 2023-03-01
150
Participants Needed
20
Research Sites
258 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Clermont-Ferrand
Lead Sponsor
M
Ministry of Health, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this study is to assess the Fecal Microbiota Transplantation (FMT) efficacy in the prevention of allogeneic hematopoietic stem cell transplantation (allo-HSCT) complications and particularly Graft versus Host Disease (GvHD). The hypothesis of this study is that allogeneic FMT may improve outcomes of these patients.
CONDITIONS
Official Title
Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 or over
- Men and women
- Patients affiliated with a social-security organization
- Patients undergoing a myelo-ablative allo-HSCT for a controlled haematologic malignant disease, with peripheral stem cells, whatever the type of donor (except cord blood)
- Signed and dated informed consent
You will not qualify if you...
- Tumor progression at the time of allo-HSCT
- Inability to understand the protocol due to language or cognitive issues
- Medical history of another progressive cancer or occurrence in the past 3 years (except basal cell carcinoma)
- Presence of serious uncontrolled diseases such as severe cardiac, renal, hepatic, or respiratory failure or severe sepsis
- Fecal incontinence
- Participation in another clinical trial involving allograft procedures, immunosuppression, GvHD treatments, or FMT for other indications
- Pregnant women
- Patients under guardianship, curatorship, or legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 20 locations
1
Service d'Hématologie Clinique et Thérapie Cellulaire CHU Amiens Picardie - Site Sud
Amiens, France
Not Yet Recruiting
2
Service Maladies du sang CHU Angers
Angers, France
Not Yet Recruiting
3
Hématologie clinique CHU Besançon
Besançon, France
Not Yet Recruiting
4
Plateforme d'Investigation Clinique / Centre d'Investigation Clinique - Inserm 1405, CHU Gabriel Montpied Clermont-Ferrand
Clermont-Ferrand, France
Actively Recruiting
5
Service de thérapie Cellulaire et d'Hématologie Clinique Adulte CHU Estaing - Clermont-Ferrand
Clermont-Ferrand, France
Not Yet Recruiting
6
Service hématologie CHU Grenoble
Grenoble, France
Not Yet Recruiting
7
Service des Maladies du sang Hôpital HURIEZ, CHRU de Lille
Lille, France
Not Yet Recruiting
8
Service de thérapie cellulaire et l'hématologie clinique adulte CHU Limoges
Limoges, France
Not Yet Recruiting
9
Service d'Hématologie Centre Hospitalier Lyon Sud
Lyon, France
Not Yet Recruiting
10
Service d'Hématologie et de Médecine interne Hôpital Brabois CHRU Nancy
Nancy, France
Not Yet Recruiting
11
Service d'Hématologie Clinique CHU Nantes
Nantes, France
Not Yet Recruiting
12
Service d'hématologie clinique, département de greffe de moelle CHU Nice
Nice, France
Not Yet Recruiting
13
Service d'Hématologie Adultes Hôpital Necker
Paris, France
Not Yet Recruiting
14
Service d'Hématologie clinique Hôpital Pitié-Salpêtrière
Paris, France
Not Yet Recruiting
15
Service d'hématologie greffe Hôpital St Louis
Paris, France
Not Yet Recruiting
16
Hématologie clinique et thérapie cellulaire Hôpital Haut-Lévèque
Pessac, France
Not Yet Recruiting
17
Service d'hématologie greffe Hôpital St Louis
Poitiers, France
Not Yet Recruiting
18
Département d'hématologie CAC Rouen
Rouen, France
Not Yet Recruiting
19
Hématologie clinique Institut de Cancérologie de la Loire
Saint-Etienne, France
Not Yet Recruiting
20
IUC T - Oncopôle
Toulouse, France
Not Yet Recruiting
Research Team
L
Lise LACLAUTRE
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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