Actively Recruiting
Faecal Microbiota Transplantation for Liver Cirrhosis
Led by University of Aarhus · Updated on 2025-01-24
220
Participants Needed
1
Research Sites
308 weeks
Total Duration
On this page
Sponsors
U
University of Aarhus
Lead Sponsor
A
Aarhus University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose is to investigate the effect of faecal microbiota transplantation (FMT) on complications, progression, and mortality of patients with liver cirrhosis. Further, the investigators want to examine the impact of FMT on the gut microbiota, gut barrier function, systemic inflammation, and immune function.
CONDITIONS
Official Title
Faecal Microbiota Transplantation for Liver Cirrhosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-75 years
- Diagnosis of liver cirrhosis with Child-Pugh score less than or equal to 12
- Acute decompensation requiring intervention such as ascites, gastrointestinal bleeding, infections leading to progressive liver failure, hepatic encephalopathy, or alcoholic hepatitis
You will not qualify if you...
- More than one organ failure defined by CLIF-SOFA score
- Untreated malignancy except non-melanoma skin cancer
- Untreated viral hepatitis
- HIV infection
- Inflammatory bowel disease
- Celiac disease
- Clostridioides difficile infection
- Pregnancy
- Unable to participate based on medical judgment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Hepatology and Gastroenterology, Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
Research Team
K
Karen Louise Thomsen, PhD
CONTACT
S
Sidsel Støy, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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