Actively Recruiting

Age: 14Years +
All Genders
Healthy Volunteers
ID06655415

Family Members At Increased Risk for Developing Inflammatory Bowel Disease (FIND-IBD) Registry Study

Led by Massachusetts General Hospital · Updated on 2024-12-20

50

Participants Needed

1

Research Sites

519 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying first-degree relatives of people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, because these relatives have a higher chance of developing IBD themselves. The study aims to understand whether behaviors, diet, and biological markers can help predict who will develop IBD and explore ways to prevent it in these high-risk individuals. This research is designed as a long-term registry lasting about 10 years or more. Participants will be asked to complete questionnaires once a year and provide samples of blood, stool, and urine. Some parts of the study, like questionnaires and stool and urine collection, can be done at home. However, blood samples must be collected at Massachusetts General Hospital. There are no drugs or treatments being tested; instead, the study observes participants over time. Throughout the study, participants will have annual assessments including questionnaires and biological sample collection to monitor for the development of IBD. Researchers will track how many participants develop IBD over the course of the study, which is anticipated to last around 10 years. This long follow-up helps scientists learn more about the factors linked to IBD onset and support early detection and prevention strategies.

CONDITIONS

Official Title

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

Who Can Participate

Age: 14Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to give informed consent
  • Ability to complete all study visits and study-related procedures
  • Ability to understand and complete study questionnaires
  • Must have at least one first-degree relative with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or IBD-unclassified)
  • Age 14 years or older
Not Eligible

You will not qualify if you...

  • Individuals with existing diagnoses of inflammatory bowel disease (ulcerative colitis, Crohn's disease, or IBD-unclassified)
  • Evidence of clinical signs or symptoms of IBD, identified during pre-screening interview

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

E

Emily W Lopes, MD, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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