Actively Recruiting

Age: 18Years - 70Years
All Genders
NCT07498933

FAP-targeted PET/NIR in Lung Malignant Tumors

Led by Peking University People's Hospital · Updated on 2026-04-01

200

Participants Needed

1

Research Sites

134 weeks

Total Duration

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AI-Summary

What this Trial Is About

Single center, prospective, diagnostic study. Patients with stage II-IIIB resectable NSCLC diagnosed by pathology were included. After receiving standard neoadjuvant therapy (chemotherapy/immunotherapy/combination therapy), FAPI-PET/CT and fluorescence imaging were performed one week before surgery. During the surgery, a near-infrared fluorescence navigation system was used to locate the tumor lesion. After surgery, the tumor bed range was determined by pathological gold standards (HE staining+immunohistochemistry), and the predictive efficacy and localization accuracy of FAPI-PET/fluorescence were compared and analyzed.

CONDITIONS

Official Title

FAP-targeted PET/NIR in Lung Malignant Tumors

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 70 years old
  • Have complete clinical and imaging data
  • Prior biopsy pathology confirmed lung cancer before neoadjuvant therapy
  • Able to provide sufficient tumor tissue for testing and research
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • History of other malignant tumors or prior anti-tumor treatments
  • Insufficient tumor tissue collected for testing and research
  • Neoadjuvant therapy duration less than 3 cycles
  • Poor quality or missing multimodal probe PET dynamic scan images
  • Lack of clinical and imaging data
  • Considered inappropriate for participation by other researchers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

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Research Team

K

Kezhong Chen, MD

CONTACT

Q

Qingyun Liu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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