Actively Recruiting
FAPI PET for Lung Fibrosis
Led by University of California, Los Angeles · Updated on 2025-07-03
30
Participants Needed
1
Research Sites
263 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective exploratory biodistribution study in patients with interstitial lung disease (ILD). The purpose of this research study is to determine where and to which degree the FAPI tracer (68Ga-FAPI-46) accumulates in normal and fibrotic lung tissues of patients with interstitial lung disease. The study will include patients with interstitial lung disease who have or will initiate a new ILD medication OR will undergo tissue biopsy or surgery of the lung. The study will include 30 patients, the upper limit for PET imaging studies conducted under the Radioactive Drug Research Committee (RDRC) purview. Participants will be injected with up to 7 mCi of 68-GaFAPi and will undergo one PET/CT scan and one High Resolution CT of the lungs. The study is sponsored by Ahmanson Translational Theranostic Division at UCLA.
CONDITIONS
Official Title
FAPI PET for Lung Fibrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with interstitial lung disease confirmed by CT scan at time of staging
- Patients who have started or will start a new ILD medication within 3 months of enrollment OR patients scheduled for lung biopsy or surgery
- Patients aged 18 years or older at time of radiotracer administration
- Patients able to provide written informed consent
You will not qualify if you...
- Pregnant or nursing patients
- Patients with active infectious lung disease
- Patients unable or unwilling to comply with study procedures or understand the trial requirements
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
S
Stephanie Lira
CONTACT
C
Contreras M Maria, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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