Actively Recruiting
FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease
Led by University of Miami · Updated on 2026-05-01
120
Participants Needed
1
Research Sites
159 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether a dietary approach that includes prolonged overnight fasting, guided by a Mediterranean-style eating pattern, is feasible for patients with myeloma precursor disease or newly diagnosed multiple myeloma.
CONDITIONS
Official Title
FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older.
- Any sex/gender.
- Able to provide consent.
- Able to speak, read, and understand English or Spanish.
- Diagnosis of Monoclonal Gammopathy of Undetermined Significance (MGUS), Smoldering Multiple Myeloma (SMM), or Multiple Myeloma (MM) per standard criteria.
- For MGUS and SMM: confirmed diagnosis.
- For MM: confirmed new diagnosis and initiating anti-myeloma therapy.
- Receiving anti-myeloma therapy at Sylvester Comprehensive Cancer Center or University of Miami Health System.
- Approval from treating oncologist.
- Eastern Cooperative Oncology Group (ECOG) Performance Status grade less than 2 (PI approval if ECOG 2 or higher).
- Not regularly fasting for 12 or more hours per night in the past 3 months.
- Not meeting two or more Mediterranean diet goals (3+ vegetable servings/day, 3+ servings of beans/legumes/week, 1+ serving of nuts/day) in prior 3 months.
- Internet access on a smartphone, tablet, or computer.
- Willing to be randomized to intervention or waitlist-control group.
You will not qualify if you...
- Younger than 18 years of age.
- Unable to provide consent.
- Unable to read or understand English or Spanish.
- Any physician-determined contraindication for diet changes.
- History of a clinical eating disorder.
- History of dementia or major psychiatric disease.
- History of stroke, myocardial infarction, or congestive heart failure within the past year.
- History of autoimmune disease currently under treatment.
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Miami
Miami, Florida, United States, 33136
Actively Recruiting
Research Team
G
Grey Freylersythe, BS
CONTACT
M
Michelle Armogan, MHA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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