Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
NCT06748963

Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

Led by University of Alberta · Updated on 2026-05-08

20

Participants Needed

1

Research Sites

117 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

A

Alberta Diabetes Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.

CONDITIONS

Official Title

Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of type 1 diabetes for 5 or more years
  • Treatment with an insulin pump without changes for over 2 months and willingness to share continuous glucose monitor data
  • Using rapid or ultra-rapid acting insulin analogs
  • HbA1c level between 7.0% and 9.9%
  • Body mass index (BMI) of 25 kg/m2 or above
  • Waist circumference indicating central obesity as per Diabetes Canada definition (94cm for some males, 90cm for other males, 80cm for females)
  • No history of stroke, heart attack, or coronary artery disease
  • Not wearing implantable devices such as pacemakers, neurostimulators, or certain magnetic implants
  • Using a continuous glucose monitor in routine diabetes management
Not Eligible

You will not qualify if you...

  • Major complications in the last 3 months, such as severe hypoglycemia needing help, diabetic ketoacidosis, or cardiovascular events
  • Limitations to aerobic or resistance exercise due to severe diabetes complications or other conditions like severe arthritis
  • Uncontrolled high blood pressure (over 160 mmHg systolic or 100 mmHg diastolic)
  • Presence of implanted devices or conditions that prevent MRI use
  • Current pregnancy or breastfeeding
  • Inability to give consent
  • Use of injection-based insulin therapy instead of insulin pump

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Alberta

Edmonton, Alberta, Canada, T6G 2E1

Actively Recruiting

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Research Team

N

Normand Boule, PhD

CONTACT

R

Reid McClure, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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