Actively Recruiting
Fasted vs. Fed State Exercise
Led by Arkansas Colleges of Health Education · Updated on 2026-03-23
40
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss. Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.
CONDITIONS
Official Title
Fasted vs. Fed State Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18-59
- Body mass index (BMI) between 25 and 45
- Healthy enough to exercise
You will not qualify if you...
- Taking medications or supplements known to affect energy expenditure
- Exercising more than once per week currently
- Actively dieting for weight loss
- Using weight loss drugs currently
- History of weight loss surgery
- Diagnosed with diabetes
- Diagnosed with heart disease including heart failure, uncontrolled hypertension, uncontrolled hypercholesterolemia, or coronary heart disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Arkansas Colleges of Health Education Research Institure Health and Wellness Center
Fort Smith, Arkansas, United States, 72916
Actively Recruiting
Research Team
K
Kyle D Flack, PhD
CONTACT
B
Blake Metcalf, DCN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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