Actively Recruiting
FDG PET-CT in Advanced Breast Cancer
Led by Samsung Medical Center · Updated on 2025-09-15
100
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective cohort study comparing metabolic response evaluation by F-18 FDG PET-CT versus conventional imaging for outcome stratification in patients with advanced breast cancer receiving first-line systemic therapy.
CONDITIONS
Official Title
FDG PET-CT in Advanced Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 19 years of age or older
- Histologically confirmed metastatic or locally advanced breast cancer with no radical topical treatment available
- If liver metastasis is present and response evaluation is difficult with bone metastasis or CT
- Presence or absence of measurable lesions according to RECIST 1.1 criteria
- Eligible for F-18 FDG PET-CT tests for treatment response evaluation per Health Insurance Review and Assessment Service
- Scheduled to start first systemic therapy for advanced breast cancer including endocrine, targeted, chemotherapy, immunotherapy, or combinations
- Willing to undergo continuous response assessments using F-18 FDG PET-CT and CE-CT (± bone scan) before treatment and at 6, 12, 24, 48 weeks after treatment
- ECOG Performance Status 0-2
You will not qualify if you...
- Previous systemic treatment for advanced breast cancer
- Contraindications to F-18 FDG PET-CT (e.g., uncontrolled diabetes) or intravenous contrast agents for CE-CT (e.g., severe allergies, severe renal dysfunction)
- Pregnancy or lactation
- Other primary malignancies unless treatment completed for radical purposes
- Medical conditions that may hinder participation or affect result interpretation
- Inability to comply with study procedures or follow-up
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Samsung medical Center
Seoul, Gannam-gu, South Korea, 06351
Actively Recruiting
Research Team
Y
Yeon Hee Park, phD
CONTACT
J
jungmin Lee, CRC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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