Actively Recruiting
Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot Study
Led by M.D. Anderson Cancer Center · Updated on 2026-03-23
30
Participants Needed
1
Research Sites
153 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn if accelerated rTMS (repetitive transcranial magnetic stimulation) can be used as a possible therapy for excessive eating.
CONDITIONS
Official Title
Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 21 to 60
- Body mass index (BMI) greater than 30 (confirmed in person)
- Able to follow verbal and written instructions in English and complete all study parts
- Have a reachable address and telephone number
- Maintain a stable residence (not a shelter, halfway house, treatment center, or group home)
- Meet safety criteria for EEG and rTMS
- Willing and able to remove metal items from neck and above for rTMS procedures
- Provide written informed consent and agree to all study procedures
- Agree to complete telehealth and in-person visits and be contacted by text
You will not qualify if you...
- rTMS treatment or research exposure within the last 6 months
- History of seizure, epilepsy, fainting, or head trauma causing loss of consciousness
- History or presence of neurological disorders such as migraine, stroke, dementia, Parkinson's disease, multiple sclerosis, or traumatic brain injury
- History of brain surgery, implanted electronic devices, or metal in the head
- Cardiac pacemakers, neural stimulators, implantable defibrillators, medication pumps, or sensors, or unstable cardiac disease
- History or current medical care for heart attack, angina, heart failure, cardiomyopathy, stroke, or transient ischemic attack
- Untreated vision problems
- Hairstyle incompatible with required EEG net
- Current or past type I diabetes
- Current insulin use
- Previous bariatric surgery
- Current enrollment in a weight loss program
- Use of medications or supplements for weight or appetite control
- History or current diagnosis of mental health conditions
- Insomnia with less than 4 hours of sleep per night on 3 or more nights per week in the last 3 months
- Less than 4 hours of sleep on the day of the visit
- Daily marijuana use
- Use of illicit drugs (other than marijuana) or non-medical prescription drug use in the last 12 months
- Current treatment for substance use disorder
- Excessive alcohol consumption (females more than 7 drinks, males more than 14 drinks per week in last 30 days)
- Use of investigational, anti/pro-convulsive, psychotropic, seizure-risk increasing, or smoking cessation medications in last 3 months
- Pregnancy or lactation
- Allergies to chocolate or M&M candy ingredients
- Noise-induced hearing loss or tinnitus
- Participation in another research study
- Any medical or psychiatric condition or medication that may affect safety or treatment, as judged by the investigator
- Considered unsuitable by the investigator for other reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
F
Francesco Versace, PHD, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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