Actively Recruiting
Feasibility and Acceptability of an Intervention to Support People With Severe Mental Illness in South Africa
Led by University of KwaZulu · Updated on 2026-01-14
86
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
U
University of KwaZulu
Lead Sponsor
C
Columbia University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Despite commendable progress in developing mental health systems in low-and-middle income countries, critical gaps remain, particularly the development of community-based systems of support for people living with severe mental illness (SMIs). This application will pilot a co-developed health system strengthening intervention programme in a South African district in order to determine its feasibility, appropriateness and limited efficacy in reducing readmission following discharge from acute psychiatric hospitalization. By generating preliminary data on the real-world implementation of a co-developed programme in low-resource contexts in South Africa, this application seeks to build on an existing foundation of research partnerships and local government collaboration to develop a transitional support intervention that could yield significant and tangible impacts on people living with SMIs in low-resource communities.
CONDITIONS
Official Title
Feasibility and Acceptability of an Intervention to Support People With Severe Mental Illness in South Africa
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years and above
- Currently admitted to a psychiatric ward for acute psychiatric treatment with ICD diagnoses including schizophrenia, delusional disorders, mood disorders with psychosis, bipolar disorder with psychotic symptoms, or severe depressive episodes with psychotic symptoms
- Determined by psychiatrist to be ready for discharge to community settings
- Willing and able to participate in the intervention programme
- Resides with a caregiver such as a family or household member
- Resides within the geographic boundaries of uMgungundlovu district
You will not qualify if you...
- Under 18 years of age
- Active suicidal thoughts
- Primary diagnosis of substance abuse or dependence
- Diagnosed personality disorders
- Serious cognitive or sensory impairments preventing informed consent or reliable assessment
- Does not reside with a caregiver
- Does not reside within the uMgungundlovu district
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Msunduzi Local Municipality
Pietermaritzburg, KwaZulu-Natal, South Africa, 3201
Actively Recruiting
Research Team
A
André Janse van Rensburg, PhD
CONTACT
T
Tasneem Kathree, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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