Actively Recruiting
Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension
Led by Northumbria University · Updated on 2026-02-06
70
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
N
Northumbria University
Lead Sponsor
H
HealthWorks Newcastle Upon Tyne
Collaborating Sponsor
AI-Summary
What this Trial Is About
High blood pressure (hypertension) is a leading risk factor for cardiovascular diseases and may contribute to poor health and premature death. The purpose of this research is to learn if a home-based isometric exercise programme combined with lifestyle change advice is a practical and acceptable method for people diagnosed with hypertension to manage their condition. Isometric exercise involves a muscle contraction without movement of the limbs and previous research has shown this may be effective for reducing blood pressure. Therefore, this study will explore the experiences, thoughts, attitudes, and barriers to participation. It will also examine the effect the isometric exercise has on blood pressure. Participants will undertake an isometric exercise programme using a wall squat position, 3 times per week, for 12 weeks. The exercise sessions will be completed at home with remote online supervision by an exercise professional. Lifestyle change advice will given in line with current guidelines to promote healthy behaviours to reduce high blood pressure. After 12 weeks, participants will be encouraged to continue with the wall squat exercise for a further 12-weeks unsupervised. Throughout the study, participants' blood pressure and daily activity will be recorded using a smartwatch device. Upon completion of the intervention period, participants will be interviewed to gather their views and opinions on the isometric exercise programme. Changes in blood pressure will be evaluated at 12 and 24 weeks. By exploring whether an isometric exercise programme is a feasible and acceptable method for hypertensive people to manage their condition and how this influences blood pressure, this research may aid in the development of a strategy to manage hypertension.
CONDITIONS
Official Title
Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of arterial hypertension according to NICE guidelines
- Currently treated with antihypertensive medication with stable type and dose for at least four months
- Office blood pressure below 180 mmHg systolic and below 110 mmHg diastolic
- Not engaged in any structured or supervised exercise program (resistance, aerobic, or isometric) at least twice weekly for the past three months
- Provided written informed consent
You will not qualify if you...
- Body mass index over 35 kg/m2
- Presence of cardiovascular disease other than hypertension
- Known orthopedic, musculoskeletal, or neurological conditions limiting isometric exercise
- Presence of secondary hypertension
- Inability to follow verbal instructions or complete the study protocol
AI-Screening
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Trial Site Locations
Total: 1 location
1
Northumbria University
Newcastle upon Tyne, United Kingdom, NE1 8ST
Actively Recruiting
Research Team
H
Helen Llewellyn, MSc
CONTACT
G
Gabriel Cucato, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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