Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07213479

Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension

Led by Northumbria University · Updated on 2026-02-06

70

Participants Needed

1

Research Sites

104 weeks

Total Duration

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Sponsors

N

Northumbria University

Lead Sponsor

H

HealthWorks Newcastle Upon Tyne

Collaborating Sponsor

AI-Summary

What this Trial Is About

High blood pressure (hypertension) is a leading risk factor for cardiovascular diseases and may contribute to poor health and premature death. The purpose of this research is to learn if a home-based isometric exercise programme combined with lifestyle change advice is a practical and acceptable method for people diagnosed with hypertension to manage their condition. Isometric exercise involves a muscle contraction without movement of the limbs and previous research has shown this may be effective for reducing blood pressure. Therefore, this study will explore the experiences, thoughts, attitudes, and barriers to participation. It will also examine the effect the isometric exercise has on blood pressure. Participants will undertake an isometric exercise programme using a wall squat position, 3 times per week, for 12 weeks. The exercise sessions will be completed at home with remote online supervision by an exercise professional. Lifestyle change advice will given in line with current guidelines to promote healthy behaviours to reduce high blood pressure. After 12 weeks, participants will be encouraged to continue with the wall squat exercise for a further 12-weeks unsupervised. Throughout the study, participants' blood pressure and daily activity will be recorded using a smartwatch device. Upon completion of the intervention period, participants will be interviewed to gather their views and opinions on the isometric exercise programme. Changes in blood pressure will be evaluated at 12 and 24 weeks. By exploring whether an isometric exercise programme is a feasible and acceptable method for hypertensive people to manage their condition and how this influences blood pressure, this research may aid in the development of a strategy to manage hypertension.

CONDITIONS

Official Title

Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of arterial hypertension according to NICE guidelines
  • Currently treated with antihypertensive medication with stable type and dose for at least four months
  • Office blood pressure below 180 mmHg systolic and below 110 mmHg diastolic
  • Not engaged in any structured or supervised exercise program (resistance, aerobic, or isometric) at least twice weekly for the past three months
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Body mass index over 35 kg/m2
  • Presence of cardiovascular disease other than hypertension
  • Known orthopedic, musculoskeletal, or neurological conditions limiting isometric exercise
  • Presence of secondary hypertension
  • Inability to follow verbal instructions or complete the study protocol

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Trial Site Locations

Total: 1 location

1

Northumbria University

Newcastle upon Tyne, United Kingdom, NE1 8ST

Actively Recruiting

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Research Team

H

Helen Llewellyn, MSc

CONTACT

G

Gabriel Cucato, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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