Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission.
S H Goodman, I H Gotlib
https://pubmed.ncbi.nlm.nih.gov/10467895/Actively Recruiting
Led by Weill Medical College of Cornell University · Updated on 2026-02-27
75
Participants Needed
1
Research Sites
8 weeks
Total Duration
This research aims to assess the feasibility and acceptability of the Maya Perinatal Cognitive Behavioral Skills App among pregnant and postpartum individuals experiencing mood, anxiety, or stress difficulties. These mental health challenges are common in the perinatal period and can impact the individual, their baby, and family. The app is designed to provide evidence-based strategies tailored to this population to help manage these symptoms and improve mental well-being. Participants will use the Maya Perinatal Cognitive Behavioral Skills App for six weeks, completing 12 skill-based modules adapted from cognitive behavioral therapy principles. The app includes psychoeducation, skill information, practice exercises, and homework designed specifically for perinatal mood and anxiety challenges. Participants will provide feedback on the apps content, interface, session structure, and pacing throughout the study. During the study, participants will complete questionnaires and interviews about their experience with the app, daily symptom tracking, and assessments of their mood, anxiety, and trauma symptoms. These evaluations will occur at multiple time points midpoint around 3 weeks, post-intervention about 6 weeks, and follow-up approximately 12 weeks. Researchers will measure app feasibility, acceptability, engagement, and symptom changes to inform future app improvements. The total participation duration is approximately 12 weeks.
CONDITIONS
Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals
A
Andrea Temkin-Yu, Psy.D.
G
Gail Harrison, MA
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Weill Medical College of Cornell University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Maya Cognitive Behavioral Skills Mobile App | Standard Care (Counseling or Medication) |
|---|---|---|
| What it is | A mobile application that delivers cognitive behavioral skills training designed for individuals in the pregnancy and postpartum period seeking help for anxiety or depression. The app modules provide psychoeducation, coping skill instruction, interactive exercises, and homework practice. | Standard care involves counseling or psychotherapy (such as cognitive behavioral therapy or interpersonal therapy), pharmacologic treatment with antidepressant or anxiolytic medications if appropriate, or a combination of both according to individual need. |
| Role in trial | The intervention being evaluated in the clinical trial to assess acceptability and feasibility for perinatal mood and anxiety. | Established management option for perinatal anxiety and depression in standard clinical settings, outside of research studies. |
| Primary use | Designed to help pregnant and postpartum individuals learn coping skills to manage symptoms of anxiety and depression during the perinatal period. | Used to treat perinatal depression and anxiety symptoms and improve overall function and wellbeing during pregnancy or after delivery. |
| How it is given or performed | Participants use a mobile device (smartphone or similar) to access the app modules, complete skills training, and receive push notifications as well as complete surveys at predefined study points. The app is used independently, with study team check-ins. | Typically involves in-person or telehealth sessions with a mental health provider for therapy, and/or prescription of medications by a clinician. Follow-up schedules and formats vary. |
| Evidence status | Currently under study in a clinical feasibility trial; no clinical outcomes are yet established for efficacy or benefit in this population. | Multiple studies and guidelines support the effectiveness of counseling and/or medication in reducing perinatal anxiety and depression symptoms. Clinical benefit and guideline recommendation are well established. |
| Important limitations | Evaluation is limited to feasibility and acceptability in a small, early-phase, single-group sample. No data on clinical improvement, long-term benefit, or comparative effectiveness are available yet. | Although effective, real-world access to counseling or medication can be limited by availability, provider expertise, stigma, or personal preference. Not all individuals may respond or be able to receive standard care. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (remote or in-person)
Duration - 6 weeks
Participants complete 12 skill-based sessions using the Maya Perinatal Cognitive Behavioral Skills App over 6 weeks. The app teaches evidence-based strategies tailored for perinatal mood and anxiety.
Participants engage with the app modules weekly and complete surveys and feedback at multiple points
Duration - 6 weeks
Participants provide additional feedback and complete assessments approximately 6 weeks after finishing the app treatment to evaluate ongoing acceptability and mood outcomes.
1 follow-up visit (remote or in-person) at approximately 12 weeks from enrollment
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/39874578/Weill Medical College of Cornell University
Lead Sponsor