Actively Recruiting
Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
Led by Javier Villaneuva-Meyer, MD · Updated on 2025-05-25
50
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
Sponsors
J
Javier Villaneuva-Meyer, MD
Lead Sponsor
N
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a Pilot/Phase I clinical study of hyperpolarized 13C (HP 13C) pyruvate injection that includes the acquisition of magnetic resonance (MR) data performed on participants with meningioma to evaluate metabolism and aid in the non-invasive characterization of aggressive tumor behavior
CONDITIONS
Official Title
Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Known or presumed meningioma based on imaging with measurable disease on MRI showing gadolinium enhancement at least 1 cm in diameter intracranially
- Planning surgical resection within 4 weeks (for 30 participants)
- No contraindication to MRI examinations
- Age 18 years or older
- Life expectancy greater than 12 weeks
- Karnofsky Performance Status over 60%
- Adequate renal function with creatinine less than 1.5 mg/dL within 60 days prior to imaging
- Signed informed consent acknowledging the investigational nature of the study
- Signed authorization for release of protected health information
You will not qualify if you...
- Significant uncontrolled medical illnesses that would interfere with study participation or affect response to imaging
- Uncontrolled blood pressure (systolic ≥140 mmHg or diastolic ≥90 mmHg) despite medication
- History of other cancers except non-melanoma skin cancer or cervical carcinoma in-situ, unless in remission and off therapy for at least 3 years
- Pregnant or breastfeeding women; women of childbearing potential must have a negative pregnancy test within 14 days prior to imaging and use effective contraception
- Inability to comply with study or follow-up procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
Research Team
W
Wendy Ma
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here