Actively Recruiting
Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment
Led by The University of Texas Medical Branch, Galveston · Updated on 2026-05-11
20
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the feasibility and adherence to a 12-week technology-assisted home-based strength training program for adults aged 55 to 80 with type 2 diabetes mellitus and mild cognitive impairment. These conditions often occur together in older adults, creating challenges that physical activity may help address, particularly for glucose control and cognitive function. Telehealth support is studied as a way to overcome barriers like transportation and group exercise concerns common in this population. Participants will engage in a progressive exercise program consisting of 50-minute sessions three times per week for 12 weeks. The program includes a warm-up, resistance training targeting various muscle groups, and a cool-down. Supervision shifts over time from mostly in-person during the first two weeks, to a combination of in-person and virtual sessions in weeks five to eight, and then mostly unsupervised with virtual support from weeks nine to twelve. Weekly check-ins with staff occur, and a final assessment is conducted at week thirteen. Throughout the study, participants undergo assessments of physical and cognitive function, glycemic control, and daily living activities at baseline and week thirteen. Tests include balance performance, timed walking tests, grip strength, cognitive assessments like the Montreal Cognitive Assessment, and blood draws. Researchers also evaluate how acceptable and feasible the home-based exercise program is and identify barriers to engagement through interviews. Total participation spans the 13-week intervention and evaluation period.
CONDITIONS
Brief Title
Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 55 and 80 years
- Diagnosed with type 2 diabetes mellitus for at least 5 years
- Mild cognitive impairment confirmed by Montreal Cognitive Assessment (MoCA) scores between 18 and 25
- Stable medication regimen for at least 3 months
- Physically able to participate in moderate-intensity exercise with physician clearance
- Have a caregiver or support person available to assist with technology use if needed
You will not qualify if you...
- Diagnosis of movement disorders such as multiple sclerosis or Parkinson's disease
- Diagnosis of Alzheimer's disease
- Current severe depression or major psychiatric conditions like bipolar disorder, psychosis, schizophrenia, or alcoholism
- Significant cerebral vascular disease
- Use of medications with strong effects on cognition such as antipsychotics, tricyclic antidepressants, anticonvulsants, sedatives, anxiolytics, or glucocorticoids
- Visual or hearing impairments that affect psychometric testing participation
- Significant medical illness or organ failure including hepatic or renal failure and unstable cardiac disease
- Untreated B12 deficiency or hypothyroidism (stable treatment allowed)
- Uncontrolled hypertension above specified thresholds (stable treatment allowed)
- Stage 5 renal impairment or dialysis
- Participation in another clinical trial
- Prisoner status
- Conditions making moderate-intensity exercise unsafe such as severe aortic stenosis, poorly controlled hypertension, angina, or syncope
- No available caregiver or support person for technology assistance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants complete a 12-week progressive home-based strength training exercise program with sessions three times per week. The program transitions from mostly supervised sessions at the start to mostly unsupervised sessions with virtual support by the end, including weekly staff check-ins.
Weekly check-ins and thrice-weekly exercise sessions
Duration - 1 week
At Week 13, participants undergo final assessments including repeat baseline tests, questionnaires, blood draw, DEXA scan, and a structured interview to evaluate program feasibility and adherence.
1 visit (in-person) for final assessments
Trial Site Locations
Total: 1 location
1
University of Texas Medical Branch, Galveston
Galveston, Texas, United States, 77555-0133
Actively Recruiting
Research Team
L
Liza Durgens
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here