Actively Recruiting
Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
Led by University Hospital, Toulouse · Updated on 2025-04-10
40
Participants Needed
1
Research Sites
139 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The management of colorectal cancer often requires oxaliplatin-based chemotherapy, either as part of curative treatment plans or exclusively in palliative situations. Oxaliplatin therefore plays a key role in the management of colorectal cancer. In addition to its digestive and hematological toxicity, oxaliplatin frequently induces chronic, often limiting, sensitive peripheral neuropathy. Only early discontinuation of oxaliplatin can limit the risk of clinically limiting neurotoxicity (grade ≥ 3). In oncology, managing the side-effects of treatment is an essential objective of supportive care, and is open to a variety of complementary medicines, including reflexology. This technique, derived from traditional Chinese medicine, involves stimulating reflex points on the arch of the foot.
CONDITIONS
Official Title
Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years and treated for colorectal cancer at Rangueil Hospital Digestive Oncology service
- Starting intravenous oxaliplatin chemotherapy at 85 mg/m² every two weeks
- Able to understand and respond to a self-questionnaire
- Life expectancy of 12 weeks or longer
- Signed informed consent form
You will not qualify if you...
- Pre-existing motor and/or sensory neuropathy
- Received reflexology treatment in the last 6 months
- Contraindications to reflexology such as venous thrombosis, foot trauma, wounds, or foot metastasis
- Patient under a legal protection scheme
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU de Toulouse
Toulouse, CHU de Toulouse, France, 31059
Actively Recruiting
Research Team
N
Nadim FARES, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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