Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06511934

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Led by Leigh R. Hochberg, MD, PhD. · Updated on 2025-12-01

2

Participants Needed

1

Research Sites

157 weeks

Total Duration

On this page

Sponsors

L

Leigh R. Hochberg, MD, PhD.

Lead Sponsor

B

Brown University

Collaborating Sponsor

AI-Summary

What this Trial Is About

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.

CONDITIONS

Official Title

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders
  • Complete or incomplete tetraplegia (quadriplegia)
  • Must live within a three-hour drive of the Study site
  • Prior enrollment in BrainGate2 clinical trial (NCT00912041)
Not Eligible

You will not qualify if you...

  • Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
  • Chronic oral or intravenous steroids or immunosuppressive therapy
  • Other serious disease or disorder that could seriously affect ability to participate in the study
  • (There are additional exclusion criteria)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Masssachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

L

Leigh R Hochberg, MD, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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