Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05676450

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

Led by M.D. Anderson Cancer Center · Updated on 2025-10-31

517

Participants Needed

2

Research Sites

183 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To test the feasibility of collecting cell-free DNA (cfDNA) samples from DLBCL patients before and after treatment. cfDNA is DNA traveling in your blood outside of a cell and is easily collected from blood samples drawn using the vein puncture method.

CONDITIONS

Official Title

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female patients who are at least 18 years old on the day of informed consent signing
  • Histologically confirmed diffuse large B-cell lymphoma requiring therapy
  • Ability to provide written informed consent for the study
  • Pregnant women are not included
  • Cognitively impaired adults are not included
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

MD Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

2

Cancer Therapy and Research Center at The UT Health Science Center at San Antonio

San Antonio, Texas, United States, 78229

Actively Recruiting

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Research Team

C

Chijioke Nze, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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