Actively Recruiting
Feasibility of Different Types of Exercise Training in Perimenopausal Females
Led by University of Toronto · Updated on 2025-09-09
30
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Throughout the menopause transition, women experience many symptoms (i.e., hot flashes, night sweats) that can significantly reduce their quality of life. Moreover, their risk of heart disease increases substantially. The years before menopause called "perimenopause" present a critical window of intervention to alleviate menopause symptoms and improve health outcomes. Our team is therefore interested in comparing the potential benefits of different approaches including following the Health Canada guidelines (i.e., accumulating 150 min of moderate-to-vigorous aerobic physical activity weekly); performing high-intensity interval training (HIIT), which involves alternating periods of intense exercise with periods of rest; or stretching in perimenopause. As a first step towards this goal, this study will assess how easy and enjoyable the interventions are to follow over a 6-week period. The information gained from this study will be used to perform a larger study with enough participants to assess the health and quality of life impacts of adopting these different strategies in perimenopause.
CONDITIONS
Official Title
Feasibility of Different Types of Exercise Training in Perimenopausal Females
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biological females in early or late perimenopause defined by menstrual cycle irregularity with bleeding in the last 12 months and at least a 7-day difference from usual cycle length
- Experiencing menopause symptoms such as hot flashes, night sweats, or joint stiffness
- Aged 40 years or older
- Having multiple cardiometabolic risk factors: sedentary lifestyle (<30 min moderate-vigorous physical activity per week), BMI 625 kg/m2, and waist circumference indicating abdominal obesity specific to BMI category
You will not qualify if you...
- History of reproductive surgeries including oophorectomy, hysterectomy, ablation, or gender-affirming surgery
- Diagnosis of cardiovascular disease, type 2 diabetes, non-alcoholic fatty liver disease, cancer (except non-melanoma skin cancer), respiratory disease (e.g., COPD or severe/uncontrolled asthma), uncontrolled hyper- or hypogonadism with recent medication changes, or Polycystic Ovary Syndrome
- Major signs or symptoms of cardiovascular diseases, diabetes, or renal disease
- Use of medication that could affect blood glucose
- Pregnant, postpartum less than 12 months, lactating, or breastfeeding within 3 months before study start
- Recreational smoking (e.g., tobacco)
- Actively following a low-carbohydrate diet (e.g., ketogenic, Atkins)
- Using transdermal or other exogenous hormones, including intrauterine devices
- Significant weight loss (>5 kg) in the past 3 months or currently taking weight loss medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Goldring Centre for High Performance Sport
Toronto, Ontario, Canada, M5S 2C9
Actively Recruiting
Research Team
J
Jenna Gillen, PhD
CONTACT
C
Clara Rivaya Salvadores, BKin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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