Actively Recruiting
Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan
Led by Shanghai First Maternity and Infant Hospital · Updated on 2026-02-23
56
Participants Needed
2
Research Sites
34 weeks
Total Duration
On this page
Sponsors
S
Shanghai First Maternity and Infant Hospital
Lead Sponsor
G
Gengma People's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to observe the effects of a 6-month, culturally-adapted low glycemic index-high fiber (LGI-HF) dietary on IR, androgen levels, and menstrual regularity among women with PCOS in remote areas of Yunnan Province. We hypothesize that a nutritional strategy designed for high-carbohydrate dietary habits while balancing feasibility and adherence can significantly improve patients' metabolic and reproductive parameters, thereby providing practical evidence-based guidance for long-term PCOS management in resource-limited settings
CONDITIONS
Official Title
Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women diagnosed with PCOS by Rotterdam criteria (two of three: oligo-/anovulation, hyperandrogenism, polycystic ovaries) after excluding related disorders
- Body mass index (BMI) of 24 kg/m² or higher
- Stable weight within ±2 kg for at least 3 months before enrollment
- Willingness to keep current physical activity levels during the study
- Residence in the study area for at least 6 months
You will not qualify if you...
- Pregnancy or breastfeeding
- Type 1 or type 2 diabetes
- Thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, or other metabolic endocrine disorders
- Use of hormonal contraceptives, insulin sensitizers, or anti-obesity drugs within the past 3 months
- Severe liver, kidney, or heart disease
- Gastrointestinal disorders that prevent high-fiber diets
- History of bariatric surgery
- Participation in other dietary intervention studies
- Cognitive or language impairments preventing understanding or consent
- Starting new weight-loss medications or supplements during the study period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Department of Gynaecology, Gengma People's Hospital
Gengma County, Yunnan, China, 677500
Actively Recruiting
2
Gengma People's Hospital
Lincang, Yunnan, China, 677500
Actively Recruiting
Research Team
Z
Zhiqin Chen, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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