Study of a Low Glycemic Index, High Fiber Diet for Women with Polycystic Ovary Syndrome in Remote Yunnan

What this Trial Is About

Researchers are evaluating the effects of a culturally adapted low glycemic index-high fiber LGI-HF diet on women with polycystic ovary syndrome PCOS living in remote areas of Yunnan Province. The study aims to observe changes in insulin resistance, androgen levels, and menstrual regularity over a 6-month period. This nutritional approach is designed to suit high-carbohydrate diets common in the area and balance feasibility with adherence, providing practical guidance for long-term PCOS management in resource-limited settings. The intervention includes a 24-week adaptive LGI-HF diet tailored for women with PCOS. Participants will follow the diet while maintaining their usual physical activity levels. Assessments will be conducted at the start, mid-point 12 weeks, and end 24 weeks of the intervention to evaluate metabolic and reproductive effects. During the study, participants will undergo evaluations including insulin resistance measurement using HOMA-IR at 12 weeks, fasting glucose and insulin tests, a six-hormone panel, and pelvic ultrasonography. The study monitors adherence to the diet and documents any changes in physical activity or medication use. Participants will be involved for at least 6 months, with safety and outcome measures carefully tracked throughout the period.

Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan