Monitoring End-tidal Oxygen Levels During Preoxygenation for ICU Intubation A Feasibility Study

What this Trial Is About

Researchers are studying critically ill patients in the intensive care unit ICU who need emergency intubation due to acute respiratory failure. The study evaluates whether measuring end-tidal oxygen EtO2 on a facemask is a reliable way to monitor preoxygenation compared to measuring EtO2 in the pharynx using a nasopharyngeal catheter. This is important because hypoxemia is a common complication during intubation, and current practices rely on pulse oxygen saturation, which may not accurately reflect proper oxygenation. The study involves a prospective interventional design where both facemask EtO2 and pharyngeal EtO2 are monitored simultaneously during the intubation processfrom the start of preoxygenation until successful intubation. The procedure includes placing a nasopharyngeal catheter for pharyngeal oxygen measurement and using a facemask monitor as done in operating rooms. The total duration of the study procedure per patient will not exceed one hour, including device setup. Participants will undergo continuous oxygen monitoring during intubation, with researchers recording the percentage of expired oxygen at both measurement sites. They will also track the number of patients whose pulse oxygen saturation drops below 90%. This data will help determine the reliability of facemask EtO2 monitoring in ICU patients. The trial is sponsored by Centre Hospitalier Rgional dOrlans and includes adult patients requiring intubation with preoxygenation by noninvasive ventilation.

Feasibility of End-tidal Oxygen Concentration Monitoring During Preoxygenation for Intubation in the Intensive Care Unit.