Actively Recruiting
Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma
Led by University Hospital Heidelberg · Updated on 2024-01-05
120
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Low-grade glioma (LGG) represent typically slowly growing primary brain tumors with world health organization (WHO) grade I or II who affect young adults around their fourth decade. Radiological feature on MRI is a predominantly T2 hyperintense signal, LGG show typically no contrast uptake. Radiotherapy plays an important role in the treatment of LGG. However, not least because of the good prognosis with long term survivorship the timing of radiotherapy has been discussed controversially. In order to avoid long term sequelae such as neurocognitive impairment, malignant transformation or secondary neoplasms initiation was often postponed as long as possible
CONDITIONS
Official Title
Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Histologically proven low-grade glioma
- Indication for definitive or adjuvant radiotherapy
- Ability to understand character and personal consequences of the clinical trial
- Written informed consent
You will not qualify if you...
- Previous cerebral irradiation
- Contraindication for contrast-enhanced MRI
- Neurofibromatosis
- Participation in another clinical trial with competing objectives
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Radiotherapy, University of Heidelberg
Heidelberg, Germany, 69120
Actively Recruiting
Research Team
S
Semi Harrabi, MD
CONTACT
A
Adriane Lentz-Hommertgen, Phd
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here