Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06531083

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Led by University of Alberta · Updated on 2026-04-06

30

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

A

Alberta Health services

Collaborating Sponsor

AI-Summary

What this Trial Is About

Trismus, or restricted jaw movement, can occur in individuals with head and neck cancer (HNC) undergoing surgery or radiation therapy. There is a paucity of research examining interventions for trismus. We aim to assess the feasibility of prospective surveillance and early intervention to mitigate trismus in individuals undergoing HNC treatment. Method: The investigators will conduct a pilot single group feasibility study involving 30 individuals with HNC who will be undergoing radiation therapy. Participants will be identified at the HNC new patient clinic. Participants will be seen weekly during radiation therapy and will receive early intervention including manual therapy and a device-based jaw exercise regimen if presenting with 5% or greater reduction in jaw opening compared to pre-treatment. The investigators will assess recruitment and completion rates, intervention acceptability, and data collection procedures. Descriptive statistics will summarize feasibility metrics and participant demographics. Findings will inform the design of a larger multicentre trial.

CONDITIONS

Official Title

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a diagnosis of oral, oropharyngeal, or nasopharyngeal cancer
  • Be scheduled to undergo cancer treatment that includes radiation therapy
  • Be able to read and understand English
  • Be an Alberta resident
Not Eligible

You will not qualify if you...

  • Previous surgery for the temporomandibular joint not related to head and neck cancer
  • Local cancer recurrence or metastatic disease
  • Unable to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Alberta/ Cross Cancer Institute

Edmonton, Alberta, Canada, T6G 2G4

Actively Recruiting

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Research Team

M

Margaret McNeely, PhD

CONTACT

L

Lynn Mohamad, PhDc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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