Actively Recruiting
Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus
Led by University of Alberta · Updated on 2026-04-06
30
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
Sponsors
U
University of Alberta
Lead Sponsor
A
Alberta Health services
Collaborating Sponsor
AI-Summary
What this Trial Is About
Trismus, or restricted jaw movement, can occur in individuals with head and neck cancer (HNC) undergoing surgery or radiation therapy. There is a paucity of research examining interventions for trismus. We aim to assess the feasibility of prospective surveillance and early intervention to mitigate trismus in individuals undergoing HNC treatment. Method: The investigators will conduct a pilot single group feasibility study involving 30 individuals with HNC who will be undergoing radiation therapy. Participants will be identified at the HNC new patient clinic. Participants will be seen weekly during radiation therapy and will receive early intervention including manual therapy and a device-based jaw exercise regimen if presenting with 5% or greater reduction in jaw opening compared to pre-treatment. The investigators will assess recruitment and completion rates, intervention acceptability, and data collection procedures. Descriptive statistics will summarize feasibility metrics and participant demographics. Findings will inform the design of a larger multicentre trial.
CONDITIONS
Official Title
Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a diagnosis of oral, oropharyngeal, or nasopharyngeal cancer
- Be scheduled to undergo cancer treatment that includes radiation therapy
- Be able to read and understand English
- Be an Alberta resident
You will not qualify if you...
- Previous surgery for the temporomandibular joint not related to head and neck cancer
- Local cancer recurrence or metastatic disease
- Unable to provide informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Alberta/ Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 2G4
Actively Recruiting
Research Team
M
Margaret McNeely, PhD
CONTACT
L
Lynn Mohamad, PhDc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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