Actively Recruiting
Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis
Led by University of Pittsburgh · Updated on 2026-02-09
20
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
C
Carnegie Mellon University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This pilot randomize trial tests the feasibility of administering two different exercise programs in people with knee osteoarthritis. One group receives the exercise program administered as usual, and the other group received the exercise program with resting intervals.
CONDITIONS
Official Title
Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 45 and 79 years
- Clinical diagnosis of primary, early to moderate stage knee osteoarthritis
- Body mass index less than 35 kg/m2
- Sedentary lifestyle
- Knee joint is the most painful joint in the body
- Ability to speak and understand English
- Willingness to comply with all study procedures and be available for the duration of the study
You will not qualify if you...
- Non-osteoarthritis disease of the knee
- Advanced knee osteoarthritis
- Knee injection in the past 3 months
- Major knee trauma or surgery in the past 5 years or previous knee surgery with hardware limiting cartilage assessment
- Participation in regular exercise or physical activity
- Participation in an intervention study for knee osteoarthritis
- Currently using a cane, walker, or crutches to walk
- History of cardiovascular disease or hypertension not controlled by medication
- Two or more unexplained falls in the past year
- Inflammatory, autoimmune, neurological, systemic, muscular, or connective tissue conditions affecting walking or exercise ability
- Contraindication to MRI
- Medical condition or characteristic that increases risk or prevents compliance with study procedures
- Pregnant female
- Acute or terminal illness
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
G
Gaupp
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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