Actively Recruiting

Early Phase 1
Age: 18Years - 65Years
All Genders
NCT07299734

Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System

Led by University Health Network, Toronto · Updated on 2025-12-23

7

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

Sponsors

U

University Health Network, Toronto

Lead Sponsor

C

Canadian Training Platform for Trials Leveraging Existing Networks

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cervical spinal cord injury (cSCI) can result in substantial loss of upper-limb function, with associated socio-economic impact on affected individuals and the healthcare system. Evidence suggests that non-invasive neuromodulation such as functional electrical stimulation (FES) therapy can contribute to regaining upper-limb function, which is a top priority for this population. This pilot study will involve individuals with cSCI using a device that combines augmented reality (AR) and functional electrical stimulation (FES) for 20, one-hour sessions over a 10-week period. The sessions will include upper-limb rehabilitation where individuals will interact with different objects with the aid of the AR +FES system. The primary objective is to assess safety and feasibility, measured by the absence of serious adverse events and participants' ability to independently set up and use the system. Secondary objectives include adherence to the intervention and user feedback through structured interviews. Exploratory outcomes will examine preliminary efficacy using clinical measures such as the Spinal Cord Independence Measure (SCIM) and the Graded Redefined Assessment of Strength, Sensation and Prehension (GRASSP).

CONDITIONS

Official Title

Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Chronic cervical spinal cord injury
  • Any level or severity of cervical spinal cord injury, traumatic or non-traumatic
  • Ability to carry out object manipulations with visible impairment (GRASSP Prehension Performance sub-score between 5 and 25)
Not Eligible

You will not qualify if you...

  • Any disease or injury other than spinal cord injury affecting grasping performance
  • Self-reported contraindications to functional electrical stimulation such as pacemakers, implantable defibrillators, implanted neurostimulation devices, metallic implants in stimulated areas, cardiac conditions, epilepsy, uncontrolled seizures, wounds or fractures on the target limb
  • Inability to understand the study procedures
  • Muscles that do not respond to functional electrical stimulation to produce grasping movements
  • Currently participating in another upper limb rehabilitation intervention study (regular physical and occupational therapy allowed)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Lyndhurst Centre, Toronto Rehabilitation Institute - University Health Network

Toronto, Ontario, Canada

Actively Recruiting

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Research Team

S

Sharmini Atputharaj, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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