Actively Recruiting
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
Led by MediBeacon · Updated on 2026-02-04
10
Participants Needed
1
Research Sites
55 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this study is to evaluate the safety and image quality of the investigational dye, MB-102, compared to the control dye (fluorescein sodium) in healthy and diseased eyes using fluorescent angiography for retinal vascular disease diagnosis and monitoring.
CONDITIONS
Official Title
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years, male or female
- Female participants must be non-pregnant, not of child-bearing potential, or willing to use adequate contraception during the trial
- Male participants must be willing to practice abstinence or use adequate contraception from MB-102 dosing day to at least 7 days after
- Participants willing to follow all study requirements
- Participants who have signed informed consent
- At least 5 participants must have current retinal or choroidal vascular disease
You will not qualify if you...
- Women who are pregnant, breastfeeding, or planning pregnancy during the study, or women of childbearing potential not willing to use contraception
- Participation in another interventional trial within 30 days or concurrent enrollment in other medical research affecting study results
- History of drug or alcohol abuse within the past year
- History of severe allergic reactions or anaphylactoid reactions to any allergens including MB-102, fluorescein sodium, or related products
- Prior history of seizures
- Current visually significant cataracts or other eye conditions preventing proper fundus photography
- Site personnel involved in the study or their immediate family
- Unable to tolerate eye imaging procedures
- Any unstable or clinically significant medical condition making participation unsafe
- Prior enrollment and dosing in this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Michigan Kellogg Eye Center
Ann Arbor, Michigan, United States, 48105
Actively Recruiting
Research Team
R
Richard B Dorshow, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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