Actively Recruiting

Phase Not Applicable
Age: 22Years +
All Genders
ID07147192

Feasibility Study of an Accommodating Intraocular Lens Design for Cataract Surgery

Led by Alcon Research · Updated on 2026-05-19

85

Participants Needed

4

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the safety and usability of a new intraocular lens (IOL) called AAL-FAIOL for adults who need cataract surgery in both eyes. The study is conducted in Central America and aims to compare the AAL-FAIOL lens with another lens called BAL-FAIOL. The goal is to explore how well these lenses work and how safe they are for long-term use after cataract removal. Participants will have cataract surgery in both eyes, with one eye receiving the AAL-FAIOL lens and the other eye receiving the BAL-FAIOL lens. The surgeries in the two eyes will be scheduled 14 to 35 days apart. The AAL-FAIOL lens can be adjusted after surgery using laser treatment if needed to improve vision. Both lenses are implanted during cataract surgery using a technique called phacoemulsification. During the study, participants will attend follow-up visits for about one year to monitor their eye health and vision. Researchers will check for any eye-related adverse events or complications, including any additional surgeries needed. The study will measure the overall safety of the lenses and how well participants do over this 12-month period after their surgeries.

CONDITIONS

Brief Title

Feasibility Study of an Accommodating IOL Design

Who Can Participate

Age: 22Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to understand and sign an Informed Consent Form
  • Willing and able to attend all scheduled study visits required per protocol
  • Diagnosed with bilateral cataracts requiring removal by phacoemulsification
  • Preoperative corneal astigmatism equal to or less than 1.50 diopter in both eyes
  • Other protocol-defined inclusion criteria may apply
Not Eligible

You will not qualify if you...

  • Women who are pregnant, plan to become pregnant during the study, or are breastfeeding
  • Taking medications that could increase risk or affect accommodation
  • Eye conditions such as glaucoma or ocular hypertension as specified in the protocol
  • Medical conditions that increase operative risk as specified in the protocol
  • Other protocol-defined exclusion criteria may apply

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 14 to 35 days

Participants undergo cataract surgery on one eye to receive the AAL-FAIOL device, followed by surgery on the other eye to receive the BAL-FAIOL device. The two eye surgeries are separated by 14 to 35 days.

2 surgery visits (in-person)

Post-operative Follow-up

Duration - Approximately 1 year

Participants attend follow-up visits for approximately 1 year to monitor recovery and outcomes. If needed, the AAL lens may be adjusted after surgery with a laser to improve vision.

Multiple follow-up visits over 1 year

Trial Site Locations

Total: 4 locations

1

Clinica 20/20

San José, Costa Rica

Actively Recruiting

2

Instituto Espaillat Cabral

Santo Domingo, Dominican Republic

Not Yet Recruiting

3

Centro Panamericano de Ojos / Clinica Lopez Beltran

San Salvador, El Salvador

Not Yet Recruiting

4

Panama Eye Center

Panama City, Panama

Actively Recruiting

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Research Team

A

Alcon Call Center

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

2

Frequently Asked Questions

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