Actively Recruiting

Age: 18Years +
All Genders
NCT05903430

A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION)

Led by The Christie NHS Foundation Trust · Updated on 2025-09-05

60

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine if the investigators are able to deliver highly focused, intense radiation to tumours in the abdominal region or chest cavity whilst limiting the dose to surrounding organs using a high field strength MR-Linac.

CONDITIONS

Official Title

A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • No contraindications to MRI
  • Eligible for abdominal SABR per NHSE SABR Consortium Guidelines or central lung SABR per RTOG Guidelines
  • Able to provide informed consent
  • Anticipated life expectancy greater than 6 months
  • No more than 3 oligometastatic sites treated in total
  • Performance status of 2 or less
  • Willing to attend follow-up visits and have data collected for at least 1 year
Not Eligible

You will not qualify if you...

  • Any contraindications to MRI identified after safety screening
  • Unable to tolerate MRI scans
  • Severe or uncontrolled systemic diseases making participation undesirable
  • Significant clinical disorders or lab findings making participation undesirable
  • Known active hepatitis B, hepatitis C, or HIV infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Christie NHS Foundation Trust

Manchester, United Kingdom, United Kingdom, M204BX

Actively Recruiting

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Research Team

C

Clare Griffin

CONTACT

C

Cynthia Eccles

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION) | DecenTrialz