Actively Recruiting
Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
Led by Johns Hopkins University · Updated on 2025-06-11
50
Participants Needed
1
Research Sites
572 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.
CONDITIONS
Official Title
Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy volunteers and hidradenitis suppurativa (HS) patients aged 22 to 70 years
- Healthy enough to undergo multiple skin biopsies as determined by the investigator
- Ability to provide informed consent
- Willingness and ability to follow all study procedures and attend scheduled visits
- Ability to understand and communicate with the investigator
- For HS patients: localized mild to moderate disease in the axillae with no active infection as assessed by the investigator
You will not qualify if you...
- Unable to provide informed consent
- Recently treated for skin diseases affecting clinical evaluation
- Known contraindications to selective electrothermolysis treatment
- Immunocompromised status
- Use of systemic steroids or immune modulators
- Use of blood thinners or bleeding disorders
- Any active or currently treated infections
- Significant medical history or illness making biopsy unsafe
- Noncompliance with study requirements
- Pregnancy or nursing (with hCG testing before each treatment)
- Allergy to anesthetics
- History of keloids or hypertrophic scars in the past 10 years
- Use of oral/topical antihistamines, analgesics, or medications impacting the study
- Use of medications impairing wound healing in the past 12 months
- Inability to undergo required motor strength and sensory testing for adverse event assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins School of Medicine
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
R
Ruizhi Wang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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