Actively Recruiting
Feasibility Testing of a Virtual Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment
Led by Dana-Farber Cancer Institute · Updated on 2026-01-29
21
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a 12-week virtual Tai Chi training program designed to improve balance and small nerve fiber function among cancer survivors who have chemotherapy-induced peripheral neuropathy (CIPN). This pilot trial aims to determine if the Tai Chi program is feasible and acceptable for these individuals, who often experience balance difficulties related to their condition. Participants are randomly assigned to one of two groups: the Tai Chi group or a waitlist control group. Those in the Tai Chi group attend virtual Tai Chi sessions twice weekly for 60 minutes and also perform independent Tai Chi exercises three days a week. The control group receives standard CIPN care and is offered Tai Chi training after completing the 12-week follow-up. The study includes baseline and 12-week follow-up visits. Throughout the 12 weeks, participants undergo screening, questionnaires, and sensory and functional testing to assess balance, strength, gait, mobility, pain, and neurotoxicity symptoms. Researchers track enrollment, session completion, and participant acceptability. Safety and functional outcomes are measured at baseline and after 12 weeks. The total duration of participation is approximately 12 weeks.
CONDITIONS
Brief Title
Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years old and older
- Cancer survivors with no evidence of disease
- Completed neurotoxic chemotherapy at least three months before enrollment
- Diagnosis of CIPN based on symptoms or clinical signs
- Self-reported balance difficulties or fear of falling due to CIPN
- Stable medication regimen for neuropathy or pain for at least three months
- ECOG Performance Status Scale score of 2 or less
- Willing to follow all study procedures including randomization and two visits
- Willing to avoid new pain medications during the study
- Individuals receiving endocrine or targeted/antibody therapy are eligible
You will not qualify if you...
- Received physical therapy or Tai Chi training specifically for CIPN in the past three months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person or virtual)
Duration - 12 weeks
Participants in the Tai Chi group attend virtual Tai Chi sessions twice weekly and perform independent Tai Chi sessions three days a week for 12 weeks. Participants in the waitlist group receive standard care prescribed by their physician.
1 baseline visit and virtual Tai Chi sessions 2 times per week plus independent sessions 3 times per week (Tai Chi group); 1 baseline visit (waitlist group)
Duration - 1 day
Participants complete a 12-week follow-up visit to assess outcomes after the intervention period.
1 follow-up visit (in-person or virtual)
Trial Site Locations
Total: 1 location
1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
T
Ting Bao, MD
N
Natalie Viyaran
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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