Actively Recruiting
Fecal Microbial Transplantation in Critically Ill Patients With Severe Infections.
Led by Shanghai 10th People's Hospital · Updated on 2024-05-17
110
Participants Needed
1
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fecal microbial transplantation is to transplant functional microbiota from the feces of healthy people into the gastrointestinal tract of patients, reconstruct new intestinal microbiota, and realize the treatment of intestinal and extra-intestinal diseases. Compared with ordinary commercial probiotics, FMT is more consistent with the composition of the intestinal microecological structure and can recover intestinal flora to the maximum extent and faster. FMT increases intestinal bacteria production function and helps to restore the systemic immune response so that sepsis pathogens are removed. The aim of this trial was to investigate the clinical effect of FMT in the treatment of patients with severe infections.
CONDITIONS
Official Title
Fecal Microbial Transplantation in Critically Ill Patients With Severe Infections.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with severe infections, defined as infected patients with SAFA≥2 OR APACHE score ≥15
- Aged 14 years or older
- Patients or their family members agreed to participate in this study
You will not qualify if you...
- Advanced tumors or diseases associated with systemic immunosuppression
- Pregnant women
- Patients with severe intestinal ulcer or perforation
- Unable to complete oral administration and no effective artificial feeding pipeline
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Tenth Hospital
Shanghai, China, 200000
Actively Recruiting
Research Team
Y
YuanZhuo Chen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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