Actively Recruiting
Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance
Led by Helsinki University Central Hospital · Updated on 2022-05-13
45
Participants Needed
1
Research Sites
221 weeks
Total Duration
On this page
Sponsors
H
Helsinki University Central Hospital
Lead Sponsor
T
Turku University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Previous studies have shown that stool transplantation (FMT) have positive effect in symptoms for some patients with irritable bowel syndrome (IBS). Studies have shown that it is possible by FMT to reverse the microbiome of the recipient's intestine in the direction of the microbiome of the donor. The effect on eating habits for engraftment of microbiome by FMT is unknown. The purpose of this study is to investigate whether FMT relieves FODMAP diet extension without worsening intestinal symptoms in IBS patients.
CONDITIONS
Official Title
Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults, age 18-75 years, knowledge of the Finnish language
- IBS patients diagnosed with Rome IV criteria, all IBS subtypes accepted
- Currently consuming a low FODMAP diet to control IBS symptoms
- Patient must sign the informed consent
You will not qualify if you...
- Diagnosed allergies to food components in the study dietary protocol
- Pregnancy and breastfeeding
- Antibiotic treatment less than three months prior enrolment
- Faecal incontinence, inability to retain enema
- Abuse of drugs, alcohol, or medications
- Other gastrointestinal diagnoses causing symptoms, including IBD, microscopic colitis, coeliac disease, and bile acid diarrhoea
- Severe psychiatric or neurologic condition reducing patient compliance
AI-Screening
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Trial Site Locations
Total: 1 location
1
Helsinki University Hospital
Helsinki, Helsinki and Uusimaa, Finland, 00290
Actively Recruiting
Research Team
P
Perttu Arkkila, Professor
CONTACT
P
Perttu Lahtinen, Md
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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