Actively Recruiting
Fecal Microbiota Transplantation for Liver Failure
Led by Ningbo Medical Center Lihuili Hospital · Updated on 2024-03-12
60
Participants Needed
1
Research Sites
295 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To investigate the safety, adverse reactions and therapeutic effects of fecal microbiota transplantation on patients with liver failure;to investigate the effect of fecal microbiota transplantation on the intestinal microecology and "gut-liver axis immune system" of liver failure, and further optimization of fecal microbiota transplantation technology.
CONDITIONS
Official Title
Fecal Microbiota Transplantation for Liver Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients willing to sign informed consent
- Patients aged 18 to 65 years
- Diagnosed with liver failure according to 2018 diagnostic guidelines, including acute worsening of jaundice and coagulation dysfunction on the basis of chronic liver disease
- May have complications such as hepatoencephalopathy, ascites, electrolyte disorder, infection, hepatorenal syndrome, hepatopulmonary syndrome, or other extrahepatic organ failures
- Serum total bilirubin ≥ 10 times upper limit of normal or daily increase ≥ 17.1 µmol/L
- Prothrombin activity ≤ 40% or INR ≥ 1.5
You will not qualify if you...
- Patients with severe heart failure, chronic obstructive pulmonary disease, cerebrovascular accident, nephrotic syndrome
- Patients with gastrointestinal bleeding, pulmonary infection, septicemia
- Patients with liver cancer, lung cancer, lymphoma, or other malignant tumors
- Patients on long-term anticoagulant therapy, or with mental or immune diseases
- Pregnant or lactating women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ningbo Medical Center Lihuili Hospital,Affiliated Lihuili hospital of Ningbo University
Ningbo, Zhejiang, China
Actively Recruiting
Research Team
L
lanman Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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