Actively Recruiting

Phase 1
Phase 2
Age: 7Years - 30Years
All Genders
Healthy Volunteers
NCT06290258

Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.

Led by Chang Gung Memorial Hospital · Updated on 2026-03-20

60

Participants Needed

1

Research Sites

177 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the relations between the brain-gut axis, cytokines and autism spectrum disorder. Fecal microbiota transplantation have the potentials to improve intestinal microbiota composition, regulate immunity, and then improve gastrointestinal symptoms, autistic symptoms, emotional behavior symptoms and sleep of children with autism spectrum disorder. Early intervention at school-age may even benefit development, improve cognition and prognosis.

CONDITIONS

Official Title

Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.

Who Can Participate

Age: 7Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with autism spectrum disorder by a child psychiatrist following DSM-5 criteria
  • Have gastrointestinal symptoms with a Gastrointestinal Symptoms Rating Scale score of 3 or higher
  • Aged between 7 and 30 years
  • Willing to participate and able to sign informed consent
Not Eligible

You will not qualify if you...

  • Unable to cooperate with fecal microbiota transplantation and examinations
  • Require antibiotics within 3 months before or after study due to health conditions
  • Require long-term use of proton pump inhibitors
  • Have severe physical diseases such as acute gastrointestinal diseases, severe malnutrition or underweight, immunodeficiency, severe allergies or autoimmune diseases, brain injuries, or severe organic brain diseases
  • Have severe mental illnesses such as schizophrenia or bipolar disorder
  • Used probiotics within 1 month before the study
  • Are pregnant
  • Cannot understand the study content
  • Unwilling to participate or refuse to sign informed consent
  • Deemed unsuitable for the study by the principal investigator or co-investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wei-Chih Chin

Taoyuan City, Taiwan, 333423

Actively Recruiting

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Research Team

W

Wei-Chih Chin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder. | DecenTrialz