Actively Recruiting
Female Fertility Preservation Using Ovarian Tissue Cryopreservation Before Highly Gonadotoxic Cancer Treatment
Led by Gumy-Pause Fabienne · Updated on 2022-11-02
100
Participants Needed
2
Research Sites
4413 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients. Unfortunately, cancer treatments can be harmful to the gonads and can affect reproductive and endocrine functions. While loss of fertility is a major concern for most patients, only the experimental option of ovarian tissue cryopreservation can be proposed to prepubertal girls with a high risk of infertility. For pubertal patient, cryopreservation of mature oocytes after ovarian stimulation can be offered if oncological treatment debut can be delayed. As it is often not possible, ovarian tissue cryopreservation can also be offered. Primary aims \- To cryopreserve ovarian tissue of pre or peripubertal patient who will be receiving highly gonadotoxic oncological treatment. Secondary aims * To create a database in order to record clinical and biological follow-up data * To pool resources with Fertisave Registry * To create a research biobank for future research projects Multicentric study: HUG, CHUV
CONDITIONS
Official Title
Female Fertility Preservation Using Ovarian Tissue Cryopreservation Before Highly Gonadotoxic Cancer Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric pre or peripubertal patient aged 2 months and older
- Patient with high risk of infertility due to gonadotoxic treatments such as high doses of alkylating agents, ovarian irradiation, or total body irradiation
- Multidisciplinary team agrees to propose ovarian tissue cryopreservation
You will not qualify if you...
- Patient younger than 2 months old
- Refusal of ovarian tissue cryopreservation by the patient or parents
- Treatments that are not highly gonadotoxic
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Geneva University Hospitals
Geneva, Switzerland, 1211
Actively Recruiting
2
CHUV
Lausanne, Switzerland
Actively Recruiting
Research Team
F
Fabienne Gumy-Pause, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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