Changes in Femur Bone Density After Cemented or Cementless Total Knee Replacement Using Manual or Robotic Surgery

What this Trial Is About

Researchers are studying how femur bone mineral density BMD changes before and after total knee arthroplasty TKA surgery in patients aged 55 and older. The study compares BMD changes in patients receiving either cemented or cementless knee implants and evaluates differences between surgeries done manually or with robotic assistance. The goal is to better understand bone loss patterns and how surgical methods may affect outcomes over time. Participants will undergo TKA surgery using one of four approaches cemented with manual surgery, cemented with robotic surgery, cementless with manual surgery, or cementless with robotic surgery. The cemented method involves inserting cement to fix the prosthetic, while the cementless method uses prosthetics that fit tightly without cement. Robotic surgery uses computer assistance for implant placement, whereas manual surgery relies on traditional surgical techniques. The study will follow patients for up to 26 months after surgery. During the study, participants will have bone density measured at specific regions of the distal femur and proximal tibia at 12 and 24 months post-surgery. Researchers will also assess patient-reported pain, function, and changes in leg lean mass at multiple time points including 2 weeks, 3 months, 12 months, and 24 months. These evaluations will help determine how the different surgical methods impact bone health and recovery. Safety and eligibility monitoring will be conducted throughout the study period.

Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty